As the two most successful clubs in English football it is inevitable that Liverpool and Manchester United regularly find themselves at loggerheads with each other.

The two cities have rarely been on the same page, both in sport and culturally, and it is a rivalry that shows no signs of abating any time soon.

The emergence of Bill Shankly’s side back in the 1960s challenged the usual order of things and although United hit back with their European Cup triumph in 1968, it was Liverpool who went on to dominate.

They won 12 league titles between 1973 and 1990, while the Red Devils struggled to compete. They even suffered the humiliation of relegation in 1974, although they bounced back at the first attempt.

The late 1980s saw the foundations laid for a shift in power. As the first seeds of the ‘Madchester’ music scene were being sown to change the cultural landscape, Alex Ferguson arrived at Old Trafford vowing to knock Liverpool “off their perch”.

He achieved that in spectacular fashion, dominating the newly-formed Premier League by winning the title on 13 occasions. Ferguson also won the Champions League twice along with numerous other trophies as Liverpool failed miserably to match their rivals.

United were the punters’ darlings during that period, regularly providing the best soccer spreadbetting, moneyline betting, totals and prop bets returns.

Liverpool briefly threatened a resurgence, winning the Champions League in 2005, but they consistently came up short in domestic competitions.

Ferguson’s retirement has led to a gradual shift in power once again, with United failing to repeat the successes they had enjoyed under the legendary manager.

Jurgen Klopp’s arrival at Anfield has sparked an upturn in their fortunes, although the German is yet to secure any silverware for the club. They finished behind United in the Premier League last season, but a huge summer spending spree has had the desired impact this term.

The Reds head into Sunday’s clash at Liverpool with a massive 16-point advantage over United with less than half the campaign completed. While Liverpool are yet to lose in the top flight this season, Jose Mourinho’s side have struggled for form and consistency.

The odds for the game tell their own story, with Liverpool strong favourites with the bookmakers to pick up three points this weekend.

However, despite the current gap between the two sides, it is worth noting that United have lost just one of their last 10 meetings with Liverpool in all competitions. Odds of 9/2 to win the game looks generous given Mourinho’s penchant for overcoming adversity.