But with Gonzalo Higuain, Paulo Dybala and Mario Mandzukic all fit, Massimiliano Allegri’s men should have little trouble prevailing against a Udinese side who suffered a 4-0 loss in the corresponding fixture last year.
High-flying Atalanta, only three points behind Napoli in fourth and sitting ahead of Lazio, Inter and AC Milan, welcome Fiorentina looking to keep fans dreaming of Champions League football for yet another week.
Lazio, one point behind Atalanta, will look to build on their impressive display against Roma away to Bologna, who have suffered two defeats and a draw since their 7-1 home rout by Napoli last month.
Inter, now 18 points off the lead, are also six behind Napoli in the third Champions League qualifying spot.
But Argentinian striker Mauro Icardi told Gazzetta dello Sport they still believe in a third-place finish.
“We’re not out of contention and we won’t be until it’s mathematically impossible for us to qualify,” he said.
“I firmly believe we can finish third, we all believe that, that’s always been our objective.”
Roma v Napoli (1400), Sampdoria v Pescara (1700), AC Milan v Chievo (1945)
Atalanta v Fiorentina (1130), Cagliari v Inter Milan, Crotone v Sassuolo, Empoli v Genoa, Torino v Palermo, Udinese v Juventus (all 1400) Bologna v Lazio (1945)