The two sides come into the match in good form with the Saints unbeaten in last eight outings in all competitions and winning six of those, while Palace are enjoying a good start to life under Alan Pardew having won all three matches since he came on board at the start of January.
Southampton needed a 1-0 replay win against Ipswich town to get into the fourth round after playing out a 1-1 draw in the first match.
Palace on the other hand trashed non-league Dover Athletic 4-0 in Pardew’s first game in charge of the Eagles.
The former Southampton and Newcastle United boss has a fully fit squad to select from for this weekend’s game with Mile Jedinak and Yannick Bolasie the only absentees due to their involvement in the Asian and African Nations Cup respectively.
Ronald Koeman, on the other hand, will be unable to call on the trio of Victor Wanyama, Morgan Schneiderlin and Toby Alderweireld as all three are sidelined with various injuries.
The Dutchman still has enough firepower in his team with Shane Long and Dusan Tadic and set to lead the Saints’ attack while 19-year-old Harrison Reed may join Eljero Elia and James Ward-Prowse in midfield.
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